Opportunity Information: Apply for CDC RFA GH19 1928

The grant opportunity titled "Consolidating Efforts Towards HIV and TB Epidemic Control in the Kenya Prisons Service (KPS) through Scale Up of High Quality HIV and TB Services, Capacity Strengthening, and Health System Strengthening under PEPFAR" is a U.S. government funding opportunity led by the Department of Health and Human Services through the Centers for Disease Control and Prevention (CDC), under PEPFAR. It is designed to expand and improve comprehensive HIV and tuberculosis (TB) services within the Kenya Prisons Service, recognizing that prisons are high-risk, high-need settings where infectious diseases can spread quickly and where continuity of care is often disrupted by transfers, releases, and limited health infrastructure. The overall intent is to reduce new HIV infections, lower HIV- and TB-related illness and deaths, and build durable systems so that prevention, care, and treatment services can be maintained at high quality over time for inmates, prison staff, staff family members, and surrounding communities.

This award is structured as a cooperative agreement, which generally means the CDC expects to have substantial involvement in the program as it is implemented, such as technical support, collaborative planning, and ongoing monitoring of progress toward targets. The opportunity is listed as discretionary funding, with activities categorized under health, and tied to CFDA number 93.067. Eligibility is described as unrestricted, meaning it is broadly open to many types of organizations (subject to any additional eligibility language that may appear in the full notice). The funding opportunity number is CDC RFA GH19-1928. At the time of posting, the opportunity anticipated up to two awards, with an award ceiling of $2,500,000. The original application closing date was October 28, 2018, with electronic submissions due by 11:59 p.m. Eastern Time.

Programmatically, the NOFO emphasizes scaling up a full package of HIV and TB prevention, testing, and treatment services tailored to a prison environment while also linking those services to the community health system. On the HIV side, a core activity area is HIV testing and counseling services (HTS), aimed at identifying people living with HIV as early as possible and linking them rapidly to care. Prevention activities include condom and lubricant programming and a range of behavioral interventions that reduce sexual transmission risk. The NOFO also includes opioid substitution therapy as part of a broader approach to prevention in contexts where substance use contributes to HIV risk, along with pre-exposure prophylaxis (PrEP) for individuals at substantial risk. It also references other sexual transmission prevention approaches, allowing implementers to apply additional evidence-based options appropriate to the setting.

Treatment and clinical care components span both adults and children, with explicit inclusion of pediatric and adult antiretroviral therapy services. The opportunity also highlights Positive Health, Dignity, and Prevention (PHDP), which typically involves supporting people living with HIV with adherence, risk reduction counseling, disclosure support where appropriate, stigma reduction, and overall wellness to improve health outcomes and reduce onward transmission. In addition, the NOFO incorporates services that often determine whether HIV programs succeed in real-world settings, such as sexual and reproductive health services, sexually transmitted infection (STI) diagnosis and treatment, and family planning. Prevention of Mother-to-Child Transmission (PMTCT) is included to ensure pregnant people living with HIV can access antiretroviral treatment and related services to protect infants from acquiring HIV, and the NOFO explicitly ties this to the goal of eliminating mother-to-child transmission of HIV (EMTCT). Voluntary Medical Male Circumcision (VMMC) is also part of the prevention package, reflecting its established effectiveness in reducing female-to-male sexual transmission of HIV in high-burden settings.

TB services are presented as a parallel priority, reflecting the close relationship between TB and HIV and the heightened transmission risks in congregate settings like prisons. The NOFO calls for TB prevention, diagnosis, and treatment, which typically involves systematic screening, prompt diagnostic testing, infection control measures, initiation of TB treatment, and careful follow-up to completion. Given the overlap between TB and HIV epidemics, the intended approach is integrated service delivery so that TB screening and care are closely linked with HIV testing and treatment, and vice versa, which helps reduce mortality among co-infected patients and improves overall outcomes.

A major feature of the opportunity is capacity strengthening and health system strengthening (HSS), paired with laboratory and strategic information (SI) activities. This reflects an understanding that service coverage alone is not enough unless systems can support quality, consistent delivery. HSS and capacity building in this context can include strengthening clinical staffing and mentorship, improving supply chain and commodity management for HIV test kits and antiretroviral medicines, enhancing clinic workflow and referral systems, and reinforcing quality improvement processes. Laboratory strengthening can involve improving access to essential testing and ensuring reliable specimen transport and results return, which are critical for timely diagnosis and treatment monitoring. Strategic information activities point to the need for strong data systems, routine monitoring, and use of data for decision-making, such as tracking testing yield, linkage to treatment, retention in care, TB case detection, treatment completion, and other key performance indicators that demonstrate progress toward epidemic control.

Continuity of care is a central requirement in the NOFO, with an explicit expectation of strong community-prison linkages. In practical terms, this means the program is not limited to what happens inside prison facilities; it must also ensure that people who enter prison already on HIV or TB treatment can continue uninterrupted, and that those diagnosed or started on treatment while incarcerated remain connected to care when they are transferred or released. It also extends to prison staff and their family members and recognizes that prisons are not isolated from surrounding communities; disease transmission and care needs move in both directions. Effective linkages generally require referral networks, shared protocols with community clinics, mechanisms for medical record transfer where feasible, discharge planning, and patient navigation approaches that reduce loss to follow-up during transitions.

The NOFO lays out clear expected outcomes that reflect PEPFAR and public health priorities. These include improved coverage and quality of HIV services in KPS settings, reduced morbidity and mortality among people living with HIV and among TB patients, and a reduced number of new HIV infections. It also emphasizes progress toward EMTCT by ensuring that PMTCT services are accessible and effective for incarcerated people and others served through KPS-linked services. Finally, the opportunity aims for long-term sustainability through a strengthened health system capable of delivering HIV and TB services reliably over time, supported by stronger capacity, better laboratory systems, and higher-quality data for continuous improvement and accountability.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Consolidating Efforts Towards HIV and TB Epidemic Control in the Kenya Prisons Service (KPS) through Scale Up of High Quality HIV and TB Services, Capacity Strengthening, and Health System Strengthening under PEPFAR" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Aug 29, 2018.
  • Applicants must submit their applications by Oct 28, 2018 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $2,500,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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